DONEE-SP is a combination of Nimesulide, Paracetamol & Serratiopeptidase and is an anti-inflammatory, analgesic and antipyretic.
Paracetamol also known as Acetaminophen, chemically named N-Acetyl-p-Aminophenol, is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer).
Serratiopeptidase is an enzyme isolated from a non-pathogenic bacteria called enterobacteria Serratia E15.
Composition:
| Each uncoated tablet contains: | ||
| Nimesulide | B.P. | 100 mg |
| Paracetamol | I.P. | 325 mg |
| Serratiopeptidase | I.P. | 15 mg |
| (as enteric coated granules) | ||
| Excipients | q.s |
MECHANISM OF ACTION:
Nimesulide is an inhibitor of cyclooxygenase so it inhibits synthesis of destructive prostaglandins and spares cytoprotective prostaglandins. Paracetamol is a valuable central analgesic but weak peripheral anti-inflammatory agent and exhibits antipyretic action. Serratiopeptidase helps to reduce pain by blocking the release of pain-inducing molecules from inflamed tissues.
DONEE-SP BOLUS
